{"id":99,"date":"2019-01-14T22:00:57","date_gmt":"2019-01-14T22:00:57","guid":{"rendered":"http:\/\/yanglab.com\/?page_id=99"},"modified":"2025-07-25T18:32:37","modified_gmt":"2025-07-25T18:32:37","slug":"publications","status":"publish","type":"page","link":"https:\/\/yanglab.com\/index.php\/home\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"99\" class=\"elementor elementor-99\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-a2d4cb4 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"a2d4cb4\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-ff77b81\" data-id=\"ff77b81\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-ce66473 elementor-widget elementor-widget-text-editor\" data-id=\"ce66473\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h2 class=\"wp-block-heading has-text-align-center\"><strong>2025<\/strong><\/h2>\n<p>Lee J<sup>+<\/sup>, Tingey M<sup>+<\/sup>, Zhang Z, Buerger F, Hong J, Zhang G, Yang M, Du B, Jeong J, Tamoyo I, Zhao Q, Hildebrandt F., He C, <strong>Yang W*<\/strong>, and Xu K* (<strong>2025<\/strong>) N6-adenosine methylation enhances nuclear mRNA export via the METTL3-NUP93 interaction. <strong><em>Nature Cell Biology<\/em><\/strong> (In revision).<\/p>\n<p>Yu W., Tingey M., Kelich J., Li Y., Yu J., Junod S., Jiang Z., Hansen I., Good N., <strong>Yang W.*<\/strong> (<strong>2025<\/strong>) Exploring Cellular Gateways: Unraveling the Secrets of Disordered Proteins within Live Nuclear Pores. <strong><em>Nature Communications<\/em><\/strong> (in revision).<\/p>\n<p>Tingey M<sup>+<\/sup>, Ruba A<sup>+<\/sup>, Junod S<sup>+<\/sup>, Rush C, Saredy J, Brew W, <strong>Yang W*<\/strong> (<strong>2025<\/strong>) Paired-Objectives Photon Enhancement (POPE) Microscopy: Doubling Photon Collection for Superior Fluorescence Imaging. <strong><em>Communications<\/em><\/strong> <strong>Engineering <\/strong>(In press).<\/p>\n<p>Junod S<sup>+<\/sup>, Rush C<sup>+<\/sup>, Tingey M, and <strong>Yang W* <\/strong>(<strong>2025<\/strong>) O-GlcNAc Modulation of Nuclear Pore Complexes Orchestrates mRNA Export Efficiency. <strong><em> PNAS<\/em><\/strong><em> (In press).<\/em><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-c22431f elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"c22431f\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-238226e\" data-id=\"238226e\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-734c5a3 elementor-widget elementor-widget-text-editor\" data-id=\"734c5a3\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h2 class=\"wp-block-heading has-text-align-center\"><strong>2024<\/strong><\/h2>\n<p>Maloney R.<sup>+<\/sup>, Junod S.<sup>+<\/sup>, Hagen K., Lewis T., Cheng C., Shajan F., Zhao M., Moore T., Truong T., <strong>Yang W.*,<\/strong> Wang R.* (<strong>2024<\/strong>) Flexible Fluorine-Thiol Displacement Stapled Peptides with Enhanced Membrane Penetration for the Estrogen Receptor\/Coactivator Interaction. <strong><em>J . <\/em><\/strong><strong><em>Biol. Chem.<\/em><\/strong> 300(12):107991.<\/p>\n<p>Tingey M., Ruba A., Jiang Z., <strong>Yang W.*<\/strong> (<strong>2024<\/strong>) Deciphering vesicle-assisted transport mechanisms in cytoplasm to cilium trafficking. <strong><em>Front.<\/em><\/strong><strong><em> Cell.\u00a0 Neurosci.<\/em><\/strong> 18:1379976. doi: 10.3389\/fncel.2024.1379976.<\/p>\n<p>Tingey, M., Junod, S. L., Rush, C., &amp; <strong>Yang, W.*<\/strong> (<strong>2024<\/strong>). Protocol for live-cell super-resolution imaging of transport of pre-ribosomal subunits through the nuclear pore complex. <strong><em>STAR protocols<\/em><\/strong>, 5(1), 102790.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-69c13ca7 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"69c13ca7\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-10a0ca0e\" data-id=\"10a0ca0e\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-30aa3a77 elementor-widget elementor-widget-text-editor\" data-id=\"30aa3a77\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\n<h2 class=\"wp-block-heading has-text-align-center\"><strong>2023<\/strong><\/h2>\n\n<p>Junod S., Tingey M., Kelich J., Goryaynov A., Herbine K., <strong>Yang W.*<\/strong> (<strong>2023<\/strong>) Dynamics of nuclear export of pre-ribosomal subunits revealed by high-speed single-molecule microscopy in live cells. <strong><em>iScience<\/em><\/strong> 26, 8, 107445, https:\/\/doi.org\/10.1016\/j.isci.2023.107445.<\/p>\n\n<p>Yu W., Rush C., Tingey M., Junod S., and <strong>Yang W.*<\/strong> (<strong>2023<\/strong>) Application of Super-resolution SPEED Microscopy in the Study of Cellular Dynamics. <strong><em>Chem. Biomed. Imaging<\/em><\/strong> 1, 4, 356\u2013371.<\/p>\n\n<p>Ruba A., Tingey M., Luo W., Yu J., Evangelou A., Higgins R., Khim S., <strong>Yang W.* <\/strong>(<strong>2023<\/strong>) The Ciliary Lumen Accommodates Passive Diffusion and Vesicle-Assisted Trafficking in Cytoplasmic-Ciliary Transport. <strong><em>Molecular Biology of the Cell<\/em><\/strong> 34(6):ar59. doi: 10.1091\/mbc.E22-10-0452. Epub 2023 Mar 1.<\/p>\n\n<p>Junod S., Tingey M., Rush C., Alkurdi A., Bajoria K., <strong>Yang W.*<\/strong> (<strong>2023<\/strong>) Obtaining 3D super-resolution images by utilizing rotationally symmetric structures and 2D-to-3D transformation. <strong><em>Computational and Structural Biotechnology Journal <\/em><\/strong>21:1424-1432.<\/p>\n\n<p>Tingey M., Ruba A., <strong>Yang W.*<\/strong> (<strong>2023<\/strong>) High\u2010speed Super\u2010Resolution SPEED Microscopy to Study Primary Cilium Signaling in vivo. <strong><em>Methods in Cell Biology<\/em><\/strong> ISSN 0091-679X, https:\/\/doi.org\/10.1016\/bs.mcb.2022.12.016<\/p>\n\n<p>Rush C, Jiang Z., Tingey M., Feng F., <strong>Yang W.* (2023)<\/strong> Unveiling the complexity: assessing models describing the structure and function of the nuclear pore complex. <strong><em>Frontiers in Cell and Development Biology<\/em><\/strong>. 11, https:\/\/doi.org\/10.3389\/fcell.2023.1245939.<\/p>\n\n<p>Tingey M., Junod S., Rush C., and <strong>Yang W.* (2023)<\/strong> Protocol for live-cell super-resolution imaging of transport of pre-ribosomal subunits through the nuclear pore complex. <strong><em>STAR Protocols.<\/em><\/strong> DOI: 10.1016\/j.xpro.2023.102790.<\/p>\n\n<h2 class=\"wp-block-heading has-text-align-center\"><strong>2022<\/strong><\/h2>\n\n<p>Tingey M., Li Y., <strong>Yang W.*<\/strong> (<strong>2022<\/strong>) Selective Degradation and Quantification of Nucleoporins in the Nuclear Pore by Auxin-inducible Degrons and Single-molecule Microscopy, <strong><em>Current Protocols<\/em><\/strong>, 2, e520. doi: 10.1002\/cpz1.520 .<\/p>\n\n<p>Islam, M.S., Junod, S.L., Zhang S., Buuh Z., Guan Y., Zhao M., Kaneria K., Kafley P., Cohen C., Maloney R., Lyu Z., Voelz V., <strong>Yang W.<\/strong> &amp; Wang R* (<strong>2022<\/strong>) Unprotected Peptide Macrocyclization and Stapling via a Fluorine-thiol Displacement Reaction. <strong><em>Nature Communications<\/em><\/strong> 13, 350.<\/p>\n\n<p>Tingey M., Schnell S.+, Yu W.+, Saredy J., Junod S., Patel D., Alkurdi A., <strong>Yang W.*<\/strong> (<strong>2022<\/strong>) Technologies Enabling Single-Molecule Super-Resolution Imaging of mRNA, <strong><em>Cells<\/em><\/strong>, 11, 3079.<\/p>\n\n<p>Tingey M., Li Y., Yu W., Young A.,<strong> Yang W.*<\/strong> (<strong>2022<\/strong>) Spelling out the roles of individual nucleoporins in nuclear export of mRNA, <strong><em>Nucleus<\/em><\/strong>, 13:1, 170-193.<\/p>\n\n<p>Tingey M. &amp; <strong>Yang W.*<\/strong> (<strong>2022<\/strong>) Unraveling docking and initiation of mRNA export through the nuclear pore complex. <strong><em>BioEssay<\/em><\/strong> 44(8):e2200027.<\/p>\n\n<p>Schnell S.J., Tingey M., <strong>Yang W.*<\/strong> (<strong>2022<\/strong>) SPEED microscopy: high-speed single-molecule tracking and mapping of nucleocytoplasmic transport. <strong><em>Methods in Molecular Biology<\/em><\/strong> 2502. Humana, New York, NY.<\/p>\n\n<h2 class=\"wp-block-heading has-text-align-center\"><strong>2021<\/strong><\/h2>\n\n<p>Li Y., <a href=\"https:\/\/www.researchgate.net\/profile\/Vasilisa_Aksenova\">Aksenova<\/a> V, Tingey M., Yu J., Ma P., Arnaoutov A., Dasso M. and <strong>Yang W.* (2021)<\/strong> Distinct roles of nuclear basket proteins in directing the passage of mRNA through the nuclear pore. <strong><em>Proc. Natl. Acad. Sci. USA<\/em><\/strong><em>, 118, (37) e2015621118.<\/em><\/p>\n\n<p>Li Y., Tingey M., Ruba A. and <strong>Yang W.* (2021)<\/strong> High-speed super-resolution imaging via SPEED microscopy and 2D to 3D transformation. <strong><em>Nature Protocols<\/em><\/strong>, 16, 532-560.<\/p>\n\n<p>Dixon C. R., Malik P., Heras J., Saiz-Ros N., Alves F., Tingey M., Gaunt E., Richardson A. C., Kelly D., Goldberg M., Towers G., <strong>Yang W.<\/strong>, Rappsilber J., Digard P., Schirmer E. C. (<strong>2021<\/strong>) STING Nuclear Partners Contribute to Innate Immune Signalling Responses. <strong><em>iScience,<\/em><\/strong> S2589-0042(21)01023-3.<\/p>\n\n<p>Tingey M., Li Y., <strong>Yang W.*<\/strong> (<strong>2021<\/strong>) Protocol for single-molecule fluorescence recovery after photobleaching microscopy to analyze the dynamics and spatial locations of nuclear transmembrane proteins in live cells, <strong><em>STAR Protocols<\/em><\/strong> <em>2, 100490, 2021.<\/em><\/p>\n\n<p>Junod S., Saredy J. and <strong><em>Yang W.*<\/em><\/strong> (<strong>2021<\/strong>) Nuclear Import of Adeno-Associated Viruses Imaged by High-Speed Single-Molecule Microscopy, <strong><em>Viruses<\/em><\/strong> 13, 167.<\/p>\n\n<p>Schnell S.J., Tingey M., and <strong>Yang W.*<\/strong> (<strong>2021<\/strong>) SPEED microscopy: high-speed single-molecule tracking and mapping of nucleocytoplasmic transport. <strong><em>Methods in Molecular Biology<\/em><\/strong> (in press).<\/p>\n\n<h2 class=\"wp-block-heading has-text-align-center\"><strong>2020<\/strong><\/h2>\n\n<p>Li Y., Tingey M., Ruba A. and <strong>Yang W.* (2020)<\/strong> High-speed super-resolution imaging via SPEED microscopy and 2D to 3D transformation. <strong><em>Nature Protocols<\/em><\/strong> https:\/\/doi.org\/10.1038\/s41596-020-00440-x.<\/p>\n\n<p>Dixon C. R., P. Malik., J. I. de las Heras., N. Saiz-Ros., F. de Lima Alves., M. Tingey., E. R. Gaunt., Richardson C. A., Kelly D. A., Goldberg M. W., Towers., <strong>Yang W.,<\/strong> Rappsilber J., Digard P., Schirmer E. C. <strong>(2020)<\/strong> STING Nuclear Partners Contribute to Innate Immune Signalling Responses. bioRxiv https:\/\/doi.org\/10.1101\/2020.12.21.423744. submitted to <strong><em>Nature Communications<\/em><\/strong><\/p>\n\n<p>Mudumbi K.<em>, Czapiewski R., Ruba A., Junod S., Li Y., Luo W., Ngo C., Ospina V., Schirmer E.<\/em> and <strong>Yang W.*<\/strong> <strong>(2020)<\/strong> Nucleoplasmic signals promote directed transmembrane protein import simultaneously via multiple channels of nuclear pores. <strong><em>Nature Communications<\/em><\/strong> 11:2184. https:\/\/doi.org\/10.1038\/s41467-020-16033-x.<\/p>\n\n<p>Junod S., Kelich J., Ma J. and <strong>Yang W.* (2020)<\/strong> Nucleocytoplasmic transport of intrinsically disordered proteins studied by high-speed super-resolution microscopy. <strong><em>Protein Science<\/em><\/strong> 29: 1459-1472. https:\/\/doi.org\/10.1002\/pro.3845.<\/p>\n\n<p>Tingey M., Schnell S., Li Y., Junod S., Yu W., and <strong>Yang W.* (2020)<\/strong> Imaging Transmembrane Protein Transport across the Nuclear Envelope. <strong><em>A Closer Look at Membrane Proteins<\/em><\/strong>, Nova Science Publishers, edited by Simon G. Patching, pg 73-98.<\/p>\n\n<h1 class=\"wp-block-heading has-text-align-center\"><strong>2019<\/strong><\/h1>\n\n<p>Tingey M., Mudumbi K., Schirmer E. and <strong>Yang W.* (2019)<\/strong> Casting a Wider Net: Differentiating between Inner Nuclear Envelope and Outer Nuclear Envelope Transmembrane Proteins. <em><strong>Int. J. Mol. Biol.<\/strong><\/em><strong> <\/strong>20(21). pii: E5248. doi: 10.3390\/ijms20215248.<\/p>\n\n<p>Liu X., Yao L., <strong>Yang W.,<\/strong> Fei Y., Mi L. and Ma J. <strong>(2019) <\/strong>Spectroscopic fluorescent tracking of a single molecule in a live cell with a dual-objective fluorescent reflection microscope.<strong> <\/strong><em><strong>Applied Physics Express<\/strong><\/em><strong> <\/strong>12, 112007.<\/p>\n\n<p>Liu X., Wang B., Yao L., Fei Y., Mi L., Ma J and <strong>Yang W. (2019)<\/strong> 3D particle tracking using a dual-objective fluorescent reflection system with spherical aberration. <em><strong>J. Phys. D: Appl. Phys.<\/strong><\/em><strong> <\/strong>52, 385403.<\/p>\n\n<p>Ruba A., Luo W. and <strong>Yang W.* (2019)<\/strong> The Ciliary Lumen Accommodates Passive Diffusion and Vesicle Trafficking in Cytoplasmic-Ciliary Transport. <em><strong>BioRxiv<\/strong><\/em><strong> <\/strong>704213; <em>doi: https:\/\/doi.org\/10.1101\/704213<\/em>.<\/p>\n\n<p>Ruba A., Luo W., Kelich J., Tingey M. and <strong>Yang W.* (2019)<\/strong> 3D Microscopy Independent Approach for Obtaining 3D Super-resolution Information. <em><strong>J. Phys. Chem. B<\/strong> 123, 5107\u22125120.<\/em><\/p>\n\n<p>Li. Y., Junod. S., Kelich, J., <strong>Yang, W.* (2019)<\/strong> Nuclear Export of RNA Molecules Studied by SPEED Microscopy. <em><strong>Methods.<\/strong><\/em><strong><em> <\/em><\/strong><em>153, 46-62\u00a0\u00a0\u00a0<\/em><br \/>https:\/\/doi.org\/10.1016\/j.ymeth.2018.08.005.<\/p>\n\n<h1 class=\"wp-block-heading has-text-align-center\"><strong>2018<\/strong><\/h1>\n\n<p>Ruba, A., Kelich J., Jiong, M., <strong>Yang, W.* (2018)<\/strong> Reply to \u201cDeconstructing transport distribution reconstruction in the nuclear pore complex\u201d. <strong><em>Nature Structural &amp; Molecular Biology<\/em><\/strong> https:\/\/doi.org\/10.1038\/s41594-018-0162-1.<\/p>\n\n<p>Yu J., Kelich J. and <strong>Yang W.* (2018)<\/strong> Assembly of Nuclear Pore Complex. <strong><em>NAMB Volume on Nuclear-Cytoplasmic Transport<\/em><\/strong>, Weidong Yang, Editor, Springer Publisher. Chapter 1, 1-14.<\/p>\n\n<p>Li. Y., Junod. S., Kelich, J., <strong>Yang, W.* (2018)<\/strong> Nuclear Export of RNA Molecules Studied by SPEED Microscopy. <em><strong>Methods. <\/strong><\/em>https:\/\/doi.org\/10.1016\/j.ymeth.2018.08.005.<\/p>\n\n<p>Li Y., Luo W. and <strong>Yang W. * (2018)<\/strong> Signal-Regulated Nuclear Transport and Accumulation of Smad Proteins studied by High-Speed Single-Molecule Microscopy. <strong><em>Biophysical J.<\/em><\/strong> 114, 2243. https:\/\/doi.org\/10.1016\/j.bpj.2018.03.018<\/p>\n\n<p>Ruba A., Luo W. and <strong>Yang W.* (2018)<\/strong> Application of SPEED microscopy in primary cilia. <strong><em>J. Vis.\u00a0\u00a0 Exp.<\/em><\/strong> (131), e56475, doi:10.3791\/56475.<\/p>\n\n<h1 class=\"wp-block-heading has-text-align-center\"><strong>2017<\/strong><\/h1>\n\n<p>Ruba A., Kelich J., Luo W., <strong>Yang W.* (2017)<\/strong> Obtaining 3D Super-resolution Information from 2D Super-resolution Images through a 2D-to-3D Transformation Algorithm. <strong><em>BioRxiv<\/em><\/strong> 188060; https:\/\/doi: https:\/\/doi.org\/10.1101\/188060.<\/p>\n\n<p>Luo W., Ruba A., Lim R., Verhey K. and <strong>Yang W.* (2017)<\/strong> Axonemal Lumen Dominates Cytosolic Protein Diffusion inside Primary Cilium. <strong><em>Scientific Reports <\/em><\/strong>7, 15793. Https:\/\/doi:10.1038\/s41598-017-16103-z.<\/p>\n\n<p>Mudumbi, K. C., &amp; <strong>Yang, W.* (2017)<\/strong>. Determination of membrane protein distribution on the nuclear envelope by single-point single-molecule FRAP. <strong><em>Current Protocols in Cell Biology<\/em><\/strong>, 76, 21.11.1\u201321.11.13. doi: 10.1002\/cpcb.<\/p>\n\n<p>Ma J.+, Kelich J.+, Junod S. and <strong>Yang W.* (2017)<\/strong> Super-resolution Mapping of Scaffold Nucleoporins in the Nuclear Pore Complex. <strong><em>Journal of Cell Science 130<\/em><\/strong>, 1299-1306 doi:10.1242\/jcs.193912. + denotes equal contribution.<\/p>\n\n<h1 class=\"wp-block-heading has-text-align-center\"><strong>2016<\/strong><\/h1>\n\n<p>Mudumbi K., Schirmer E. and <strong>Yang W.* (2016) <\/strong>Single-point FRAP distinguishes inner and outer nuclear membrane protein distribution. <strong><em>Nature Communications<\/em><\/strong> 7:12562, DOI:10.1038\/ncomms12562.<\/p>\n\n<p>Li C., Garyaynov A. and <strong>Yang W.* (2016)<\/strong>\u00a0 The selective barrier in the nuclear pore complex. <strong><em>Nucleus<\/em><\/strong> 7:430-446.<\/p>\n\n<p>Ma J., Goryaynov A. and <strong>Yang W.* (2016)<\/strong> Super-resolution Three-dimensional Tomography of Interactions and Competitions in the Nuclear Pore Complex. <em><strong>Nature Structral &amp; Molecular Biology<\/strong><\/em> 23:239-247.<\/p>\n\n<p>Verhey K.* and <strong>Yang W. (2016)<\/strong> Permeability barriers for generating a unique ciliary protein and lipid composition. <strong><em>Current Opinion in Cell Biology <\/em><\/strong>41, 109-116.<\/p>\n\n<p>Ruba A. and <strong>Yang W.* (2016)<\/strong> O-GlcNAc-ylation in the Nuclear Pore Complex. <strong><em>Cellular and Molecular Bioengineering<\/em><\/strong> 9, 227-233.<\/p>\n\n<p>Mudumbi K. and <strong>Yang W.* (2016)<\/strong> Probing protein distribution along the nuclear envelope in vivo by using single-molecule FRAP. <strong><em>Methods in Molecular Biology<\/em><\/strong> 1411, 113-122.<\/p>\n\n<p>Ma J., Kelich J. and <strong>Yang W.* (2016)<\/strong> SPEED microscopy and its application in nucleocytoplasmic transport. <em><strong>Methods in Molecular Biology<\/strong><\/em> 1411, 503-518.<\/p>\n\n<h1 class=\"wp-block-heading has-text-align-center\"><strong>2015<\/strong><\/h1>\n\n<p>Kelich J., Ma J., Dong B., Wang Q., Chin M., Magura C., Xiao W. and <strong>Yang W.* (2015)<\/strong> Super-resolution Imaging of Nuclear Import of Adeno-Associated Virus in Live Cells. <strong><em>Molecular Therapy &#8211; Methods &amp; Clinical Development<\/em><\/strong> 2:15047. doi:10.1038\/mtm.2015.47.<\/p>\n\n<p>Mi L., Goryaynov A., Lindquist A., Rexach M. and <strong>Yang W.* (2015)<\/strong> Quantifying Nucleoporin Stoichiometry Inside Single Nuclear Pore Complexes In vivo. <strong><em>Scientific Reports<\/em><\/strong> 5:9312.<\/p>\n\n<h1 class=\"wp-block-heading has-text-align-center\"><strong>2014<\/strong><\/h1>\n\n<p>Goryaynov A. and <strong>Yang W.* (2014)<\/strong> Role of molecular charge in nucleocytoplasmic transport. <em><strong>PLoS One<\/strong><\/em>. 9(2):e88792. doi: 10.1371\/journal.pone.0088792.<\/p>\n\n<p>Schnell S., Ma J. and <strong>Yang W.* (2014)<\/strong> Three-dimensional mapping of mRNA export through the nuclear pore complex. <strong><em>Genes,<\/em><\/strong> 5, 1032-1049.<\/p>\n\n<p>Kelich J. and <strong>Yang W.* (2014)<\/strong> High-resolution imaging reveals new features of nuclear export of mRNA through the nuclear pore complex. <em><strong>Int. J. Mol. Sci. <\/strong><\/em>(Cover) 15, 14492-14504.<\/p>\n\n<h1 class=\"wp-block-heading has-text-align-center\"><strong>2013<\/strong><\/h1>\n\n<p>Ma J., Liu Z., Michelotti N., Pitchiaya S., Veerapaneni R., Androsavich J., Walter N. and <strong>Yang W.* (2013)<\/strong> High-resolution three-dimensional mapping of mRNA export through the nuclear pore. <strong><em>Nature Communications<\/em><\/strong>, 4:2414 doi:10.1038\/ncomms3414.<\/p>\n\n<p><strong>Yang W.* (2013)<\/strong> Distinct, but not completely separate spatial transport routes in the nuclear pore complex. <em><strong>Nucleus<\/strong><\/em>, 4,166-175.<\/p>\n\n<h1 class=\"wp-block-heading has-text-align-center\"><strong>2012<\/strong><\/h1>\n\n<p>Ma J., Goryaynov A., Sarma A. and <strong>Yang W.* (2012)<\/strong> Self-Regulated Viscous Channel in the Nuclear Pore Complex. <em><strong>Proc. Natl. Acad Sci.<\/strong><\/em> USA, 109, 7326-7331.<\/p>\n\n<p>Goryaynov A., Ma J. and <strong>Yang W.* (2012)<\/strong> Single-Molecule Studies of Nuclear Transport: from One Dimension to Three Dimensions. <strong><em>Integrative Biology<\/em><\/strong> (Cover) 4, 10-21.<\/p>\n\n<h1 class=\"wp-block-heading has-text-align-center\"><strong>2011<\/strong><\/h1>\n\n<p>Mi L., Xiong R., Zhang Y., Li Z., <strong>Yang W.,<\/strong> Chen J., Wang P.* <strong>(2011)<\/strong> Microscopic Observation of the Intercellular Transport of CdTe Quantum Dot Aggregates Through Tunneling-Nanotubes. <strong><em>JBNB<\/em><\/strong>, 2, 172-179.<\/p>\n\n<p>Sarma A. and <strong>Yang W.* (2011)<\/strong> Calcium-Regulation of Nucleocytoplasmic Transport. <strong><em>Protein &amp; Cell<\/em><\/strong>, 2, 291-302.<\/p>\n\n<p><strong>Yang W.* (2011)<\/strong> \u2018&#8217;Natively Unfolded\u2019&#8217; Nucleoporins in Nucleocytoplasmic Transport: Clustered or Evenly Distributed? <em><strong>Nucleus<\/strong><\/em>, 2, 10-16.<\/p>\n\n<h1 class=\"wp-block-heading has-text-align-center\"><strong>2010<\/strong><\/h1>\n\n<p>Ma J. and <strong>Yang W.* (2010)<\/strong> Three-Dimensional Distribution of Transient Interactions in the Nuclear Pore Obtained by Single-Molecule Snapshots. <em><strong>Proc. Natl. Acad. Sci.<\/strong><\/em> USA, 107, 7305-7310.<\/p>\n\n<p>Goryaynov A., Sarma A, Ma J. and <strong>Yang W.* (2010)<\/strong> Single-Molecule Imaging of Nuclear Transport.<em><strong> J. Vis. Exp.<\/strong><\/em> (http:\/\/www.jove.com\/index\/Details.stp?ID=2040).<\/p>\n\n<h1 class=\"wp-block-heading has-text-align-center\"><strong>2008<\/strong><\/h1>\n\n<p>Sun, C., <strong>Yang, W.,<\/strong> Tu, L.-C. and Musser, S. M.* <strong>(2008)<\/strong> Single Molecule Measurements of Importin Alpha\/Cargo Complex Dissociation at the Nuclear Pore. <em><strong>Proc. Natl. Acad. Sci.<\/strong><\/em> USA, 105, 8613-8618.<\/p>\n\n<h2 class=\"wp-block-heading has-text-align-center\"><strong>Selected Publications Before 2007<\/strong><\/h2>\n\n<p><strong>Yang W.<\/strong> and Musser M. S.* <strong>(2006)<\/strong> Nuclear transport time and efficiency are dependent on importin \u00a0concentrations. <strong><em>Journal of Cell Biology<\/em><\/strong>, 174, 951-961.<\/p>\n\n<p><strong>Yang W.<\/strong> and Musser M. S. <strong>(2006)<\/strong> Visualizing single molecules transiting through nuclear pore complexes using narrow-field epifluorescence microscopy. <em><strong>Methods<\/strong><\/em>, 39, 316-328.<\/p>\n\n<p>Wang P. N., <strong>Yang W.<\/strong>, et al. <strong>(2004)<\/strong> Photoluminescence from High Purity InN and InGaN Nanoparticles Synthesized by Pulsed Discharge.<strong><em> Focus on Nanotechnology Research<\/em><\/strong>, Eugene V. Dirote (Editor), Nova Science Publisher. Chapter 8, 155-172.<\/p>\n\n<p><strong>Yang W.,<\/strong> Gelles J. and Musser M. S. <strong>(2004)<\/strong> Imaging of single-molecule translocation through nuclear pore complexes. <strong><em>Proc. Natl. Acad. Sci. <\/em><\/strong>USA, 101, 12887-12892.<\/p>\n\n<p><strong>Yang W.,<\/strong> Wang P.N., Li F.M. and Cheah K.W. <strong>(2002)<\/strong> Synthesis of oxygen-free InN nanoparticles by pulse discharge. <strong><em>Nanotechnology<\/em><\/strong>, 13, 65-68.<\/p>\n\n<h2 class=\"wp-block-heading\"><\/h2>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>2025 Lee J+, Tingey M+, Zhang Z, Buerger F, Hong J, Zhang G, Yang M, Du B, Jeong J, Tamoyo I, Zhao Q, Hildebrandt F., He C, Yang W*, and Xu K* (2025) N6-adenosine methylation enhances nuclear mRNA export via the METTL3-NUP93 interaction. Nature Cell Biology (In revision). Yu W., [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":444,"parent":90,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"ngg_post_thumbnail":0,"footnotes":""},"class_list":["post-99","page","type-page","status-publish","has-post-thumbnail","hentry"],"jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/PaD2aX-1B","_links":{"self":[{"href":"https:\/\/yanglab.com\/index.php\/wp-json\/wp\/v2\/pages\/99","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/yanglab.com\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/yanglab.com\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/yanglab.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/yanglab.com\/index.php\/wp-json\/wp\/v2\/comments?post=99"}],"version-history":[{"count":26,"href":"https:\/\/yanglab.com\/index.php\/wp-json\/wp\/v2\/pages\/99\/revisions"}],"predecessor-version":[{"id":1113,"href":"https:\/\/yanglab.com\/index.php\/wp-json\/wp\/v2\/pages\/99\/revisions\/1113"}],"up":[{"embeddable":true,"href":"https:\/\/yanglab.com\/index.php\/wp-json\/wp\/v2\/pages\/90"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/yanglab.com\/index.php\/wp-json\/wp\/v2\/media\/444"}],"wp:attachment":[{"href":"https:\/\/yanglab.com\/index.php\/wp-json\/wp\/v2\/media?parent=99"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}